If you’re on the hunt for a serum that actually delivers what it promises, you’re in the right place. We’ve rounded up the 10 best-selling serums on Amazon—customer favorites that consistently deliver real results. Whether you’re dealing with dryness, dullness, acne scars, or fine lines, there’s a serum here for every skin concern.
1. COSRX Snail Mucin 96% Power Repairing Essence
- Best For: Damaged, dehydrated, or sensitive skin
- Key Ingredients: 96% snail secretion filtrate, sodium hyaluronate, allantoin, panthenol
- Texture: Lightweight, slightly sticky essence
- Fragrance: Fragrance-free
- Why You Should Use It:
This K-beauty cult favorite is packed with snail mucin—a miracle ingredient for repairing skin, improving hydration, and soothing irritation. It helps fade acne scars, plumps up the skin, and strengthens the skin barrier without clogging pores. Perfect for sensitive and stressed skin types. - How to Use:
Apply 2–3 pumps to clean, dry skin after toner. Gently pat in until fully absorbed. Follow with moisturizer.
2. TruSkin Vitamin C Serum
- Best For: Brightening, anti-aging, and dark spot reduction
- Key Ingredients: Vitamin C (Sodium Ascorbyl Phosphate), hyaluronic acid, vitamin E, witch hazel, jojoba oil
- Texture: Lightweight, watery serum
- Fragrance: Subtle citrus scent
- Why You Should Use It:
This serum is beloved for its ability to even out skin tone, brighten dull skin, and reduce signs of aging. Its antioxidant-rich formula helps fight sun damage and environmental stress. It also boosts collagen for a firmer look. - How to Use:
Apply 3–5 drops to clean skin in the morning. Let it absorb before applying moisturizer and sunscreen.
3. CeraVe Resurfacing Retinol Serum
- Best For: Acne scars, uneven skin texture, post-inflammatory hyperpigmentation
- Key Ingredients: Encapsulated retinol, niacinamide, ceramides, licorice root extract
- Texture: Silky, lightweight gel-serum
- Fragrance: Fragrance-free
- Why You Should Use It:
CeraVe’s gentle retinol serum is ideal for beginners. It smooths skin texture, fades acne marks, and supports the skin barrier with ceramides. It’s effective without causing major irritation—great for daily use. - How to Use:
Use at night after cleansing and toning. Apply a small amount and follow with a moisturizer. Always wear sunscreen in the morning.
4. Eva Naturals Vitamin C Serum with Hyaluronic & Ferulic Acid
- Best For: Brightening, anti-aging, and reducing sun spots
- Key Ingredients: Vitamin C, hyaluronic acid, ferulic acid, vitamin E, niacinamide, salicylic acid
- Texture: Thin and fast-absorbing
- Fragrance: Light herbal scent
- Why You Should Use It:
This multitasking serum combines powerful brightening and hydrating agents with mild exfoliation. It helps improve skin tone, reduce fine lines, and fade dark spots. Ideal for people who want visible results with natural ingredients. - How to Use:
Apply a few drops to the face after cleansing. Use once daily, preferably in the morning.
5. Good Molecules Hyaluronic Acid Serum
- Best For: Daily hydration and plumping
- Key Ingredients: Hyaluronic acid, glycerin, purified water
- Texture: Clear, slightly viscous liquid
- Fragrance: Fragrance-free
- Why You Should Use It:
A simple, effective hydrator that suits all skin types—especially dry or dehydrated skin. It instantly plumps and softens the skin while prepping it to better absorb other products. It’s a staple in any skincare routine. - How to Use:
Apply to damp skin after cleansing and toning. Follow with moisturizer to seal in hydration.
6. Anua 10% Niacinamide + 4% Tranexamic Acid Serum
- Best For: Brightening, hyperpigmentation, sensitive skin
- Key Ingredients: Niacinamide, tranexamic acid, licorice extract, panthenol
- Texture: Lightweight, watery serum
- Fragrance: Fragrance-free
- Why You Should Use It:
This serum targets dark spots without irritating the skin, making it ideal for sensitive types. It reduces inflammation, soothes redness, and supports the skin barrier—all while improving overall brightness. - How to Use:
Apply a few drops to clean skin in the morning or evening. Follow with moisturizer.
7. RoC Derm Correxion Retinol Serum Stick
- Best For: Fine lines, wrinkles, and firmness
- Key Ingredients: Retinol, glycerin, shea butter
- Texture: Solid stick serum (melts on contact)
- Fragrance: Mild floral scent
- Why You Should Use It:
This innovative serum stick makes retinol application easy and targeted. It firms saggy areas, reduces crow’s feet, and smooths fine lines without drying. Its nourishing formula works overnight while you sleep. - How to Use:
Swipe directly on areas of concern (like forehead or around the eyes) at night. Follow with a moisturizer.
8. Good Molecules Discoloration Correcting Serum
- Best For: Hyperpigmentation, acne scars, uneven skin tone
- Key Ingredients: Tranexamic acid, niacinamide, glycerin
- Texture: Lightweight gel-serum
- Fragrance: Fragrance-free
- Why You Should Use It:
Specifically designed to treat discoloration, this serum works gradually but effectively. It fades marks caused by acne or sun damage and evens out skin tone with regular use. A budget-friendly option that performs. - How to Use:
Apply a small amount to problem areas after cleansing. Use daily, AM or PM.
9. The Ordinary Hyaluronic Acid 2% + B5
- Best For: Deep hydration, improving skin texture
- Key Ingredients: Multi-molecular hyaluronic acid, vitamin B5
- Texture: Slightly tacky gel
- Fragrance: Fragrance-free
- Why You Should Use It:
This cult-favorite serum draws moisture into the skin at multiple levels. It leaves skin feeling dewy and supple, especially when used consistently. Vitamin B5 also helps heal and maintain the skin barrier. - How to Use:
Apply to damp skin after toner. Use morning and night before moisturizer.
10. The Ordinary Niacinamide 10% + Zinc 1%
- Best For: Oily, acne-prone skin and enlarged pores
- Key Ingredients: Niacinamide, zinc PCA
- Texture: Semi-thick serum
- Fragrance: Fragrance-free
- Why You Should Use It:
This best-seller is ideal for anyone dealing with excess oil, breakouts, or rough texture. Niacinamide regulates sebum and tightens pores, while zinc helps calm inflammation. Visible improvements in clarity and smoothness are common. - How to Use:
Use after toner on clean skin, morning or evening. Avoid layering with pure vitamin C.
Final Thoughts
Finding the right serum doesn’t have to be a guessing game. These top 10 best-sellers are proven favorites, loved for their real results, quality ingredients, and skin-friendly formulas. Whether you’re aiming to brighten, hydrate, or fight signs of aging, there’s a perfect match here for you.
Ready to level up your skincare routine?